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Phd1 deficiency lowers O 2 consumption and induces hypoxia tolerance in skeletal muscle by altering glucose metabolism from oxidative to anaerobic, thereby reducing ROS generation whilst maintaining a basal mitochondrial respiration rate

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V Geenes C Williamson 2009 Intrahepatic cholestasis of pregnancy World J

[62] Ingestion of alcohol can initiate systemic pro-inflammatory changes through two intestinal routes: (1) altering intestinal microbiota composition (dysbiosis), which increases lipopolysaccharide (LPS) release, and (2) degrading intestinal mucosal barrier integrity thus allowing LPS to enter the circulatory system

GYY4137s slow-release kinetics enable sustained low-concentration exposure, potentially more suitable for inducing DC reprogramming compared to fast-release donors

Mary stated she occasionally drinks alcohol, but has not had a drink since she moved